Course curriculum

  • 1

    Welcome

    • Navigating the course

    • Introducing dnalife

    • Why DNA Pain

      FREE PREVIEW

    • Required reading: Understanding the importance of holistic approaches to pain management.
  • 2

    Support material

    • DNA Pain sample report

    • DNA Pain whitepaper

    • DNA Pain SNP guide
  • 3

    Introducing the science

    • Introduction to Genetics

    • Test your knowledge: Introduction to Genetics

    • Bonus material (optional): Learn Genetics

    • Bonus material (optional): What is Precision Medicine?

    • Bonus material: Optional Reading
  • 4

    Overview of the DNA Pain report

    • Overview of the DNA Pain report
  • 5

    Oxidative stress and chronic pain

    • Oxidative stress and related genes

    • Optional reading material: Oxidative stress
  • 6

    Inflammation

    • Inflammation driving chronic pain

    • Optional reading material: The role of inflammation in chronic pain
  • 7

    Methylation, chronic pain, and comorbidities

    • Methylation and its importance in chronic pain

    • Optional reading material: Methylation
  • 8

    Cell signalling

    • Cell signalling and chronic pain explained

    • Optional reading material: Cell signalling
  • 9

    The neurochemical pathway

    • The neurochemical pathway: A focus on BDNF and NPY

    • Optional reading material: The neurochemical pathway
  • 10

    The Serotonin pathway and its role in chronic pain and related comorbidities

    • Genes in the serotonergic system, chronic pain, and its comorbidities

    • Optional reading material: Serotonin
  • 11

    Catecholamines: dopamine, adrenaline and noradrenaline

    • Catecholamine production and breakdown in chronic pain

    • Optional reading material: Catecholamines in pain
  • 12

    The opioid pathway

    • Opioids and its receptors in pain management

    • Optional reading material: Opioids
  • 13

    The endocannabinoid system

    • Endocannabinoids and FAAH in chronic pain

    • Optional reading material: Endocannabinoids
  • 14

    Bonus chapter: Medcheck and pharmacogenomics

    • Introductions to Pharmacogenomics

    • Medcheck Sample Report

    • Reading: Chang 2015. Pharmacogenetics: Using Genetic Information to Guide Drug Therapy.

    • Reading: CPIC Guideline for Codeine and CYP2D6

    • Medications covered in Medcheck test

    • Medcheck Gene Monographs

    • Pharmacogenomics Online Resources
  • 15

    Practical application

    • Putting it all together
  • 16

    Test your knowledge

    • DNA Pain quiz